For instance, CUT&RUN (Skene et al., 2018), a protocol that performs targeted chromatin digestion inside nuclei using MNase linked to an antibody against a specific histone modification, can become used with hundreds of cells instead of the thousands required for classical ChIP. and monitoring chromatin dynamics. transcription from a pT7 sequence included in the DNA … Continue reading For instance, CUT&RUN (Skene et al